Recent Publications
Lab Publications
Ortiz-Mantilla S., Roesler C.P., Realpe-Bonilla T., Benasich A.A. (2023). Experience-dependent effects of passive auditory exposure in infants impact theta phase synchrony and predict later language. Cerebral Cortex. doi: 10.1093/cercor/bhad063.
Wagner M., Ortiz-Mantilla S., Rusiniak M., Benasich A.A., Shafer V.L., & Steinschneider. (2022). Acoustic‑level and language‑specific processing of native and non‑native phonological sequence onsets in the low gamma and theta‑frequency bands. Scientific Reports, 12, 314. doi.org/10.1038/s41598-021-03611-2
Ortiz-Mantilla S., Roesler C.P., Realpe-Bonilla T., & Benasich, A.A. (2021). Modulation of theta phase synchrony during syllable processing as a function of interactive acoustic experience in infancy. Cerebral Cortex. doi.org/10.1093/cercor/bhab256
Jannesari M., Saeedi A., Zare M., Ortiz-Mantilla S., Plenz D., Benasich A.A. (2020) Stability of neuronal avalanches and long-range temporal correlations during the first year of life in human infants. Brain, Structure and Function doi: 10.1007/s00429-019-02014-4.
Hämäläinen J.A., Ortiz-Mantilla S., Benasich A.A. (2019). Change detection to tone pairs during the first year of life – Predictive longitudinal relationships for EEG-based source and time- frequency measures. NeuroImage. doi: 10.1016/j.neuroimage.2019.05.034.
Ortiz-Mantilla S., Cantiani C., Shafer V., & Benasich, A.A. (2019). Minimally-verbal children with autism show deficits in theta and gamma oscillations during processing of semantically-related visual information. Scientific Reports. doi: 10.1038/s41598-019-41511-8.
Cantiani C., Ortiz-Mantilla S., Riva V., Piazza C., Musacchia G., Molteni M., Marino C., & Benasich AA. (2019). Reduced left-lateralized pattern of event-related EEG oscillations in infants at familial risk for language and learning impairment. NeuroImage Clinical. doi: 10.1016/j.nicl.2019.101778.
Ortiz-Mantilla, S., Realpe-Bonilla, T., & Benasich, A. (2019). Early interactive acoustic experience with non-speech generalizes to speech and confers a syllabic processing advantage at 9 months. Cerebral Cortex, 29, 1789-1801. doi: 10.1093/cercor/bhz001
Musacchia G., Ortiz-Mantilla S., Roesler C.P., Rajendran S., Morgan-Byrne J., & Benasich A.A. (2018). Effects of noise and age on the infant brainstem response to speech. Clinical Neurophysiology, 129(12), 2623-2634. doi: 0.1016/j.clinph.2018.08.005
Koyama, M.S., Ortiz-Mantilla, S., Roesler, C.P., Milham, M.P., & Benasich, A.A. (2017). A modulatory effect of brief passive exposure to nonlinguistic sounds on intrinsic functional connectivity: Relevance to cognitive performance. Cerebral Cortex, 27, 5817-5830. doi: 10.1093/cercor/bhx266.
Musacchia, G., Ortiz-Mantilla, S., Choudhury, N., Realpe-Bonilla, T., Roesler, C., & Benasich A.A. (2017). Active auditory exposure in infancy promotes brain plasticity in Theta and Gamma oscillations. Developmental Cognitive Neuroscience, 26, 9-19. doi: 10.1016/j.dcn.2017.04.004.
Riva, V., Cantiani, C., Benasich, A.A., Molteni, M., Piazza, C., Giorda, R., Dionne, G., & Marino, C. (2017). From CNTNAP2 to early expressive language in infancy: the mediation role of auditory processing. Cerebral Cortex, May 11, 2017, 1-9. doi: 10.1093/cercor/bhx115.
Past Publications
2016
Benasich, A.A., Choudhury, N., Peters, S., & Ortiz-Mantilla, S. (2016). Early Screening and Intervention of Infants at High Risk for Developmental Language Disorders. International Dyslexia Association (IDA). Perspectives on Language and Literacy, Winter 2016, 24-29.
Ortiz-Mantilla, S., Hämäläinen, J.A., Realpe-Bonilla, T., & Benasich A.A. (2016). Oscillatory dynamics underlying perceptual narrowing of native phoneme mapping from 6 to 12 months of age. Journal of Neuroscience, 36(48), 12095-12105. doi: 10.1523/JNEUROSCI.1162-16.2016.
Zare, M., Rezvani, Z., & Benasich, A.A. (2016). Automatic classification of 6-month-old infants at familial risk for language-based learning disorder using support vector machine. Clinical Neurophysiology, 127, 2695-2703. https://doi.org/10.1016/j.clinph.2016.03.025.
Cantiani, C., Choudhury, N.A., Yu, Y.H., Shafer, V., Schwartz, R.G., & Benasich, A.A. (2016). From sensory perception to lexical-semantic processing: An ERP study in non-verbal children with autism. PLOS ONE http:doi.org/10.1371/journal.pone.0161637
Acar, Z. A., Ortiz-Mantilla, S., Benasich, A., & Makeig, S. (2016). High-resolution EEG source imaging of one-year-old children. Conference proceedings: ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2016, 117–120. https://doi.org/10.1109/EMBC.2016.7590654
Cantiani, C., Riva, V., Piazza, C., Bettoni, R., Molteni, M., Choudhury, N., Marino, C., & Benasich, A.A. (2016). Auditory discrimination predicts linguistic outcome in Italian infants with and without familial risk for language learning impairment. Developmental Cognitive Neuroscience, 20, 23-34. doi: 10.1016/j.dcn.2016.03.002.
Tozzi, A., Zare, M., & Benasich, A.A. (2016). New perspectives on spontaneous brain activity: dynamic networks and energy matter. Frontiers in Human Neuroscience, 94(8), 702-716. doi: 10.3389/fnhum.2016.00247.
Piazza, C., Cantiani, C., Akalin-Acar, Z., Miyakoshi, M., Benasich, A.A., Reni, G., Bianchi, A.M., & Makeig, S. (2016). ICA-derived cortical responses indexing rapid multi-feature auditory processing in six-month-old infants. NeuroImage, 133, 75-87. doi:10.1016/j.neuroimage.2016.02.060
2015
Heim, S., Choudhury, N., & Benasich, A.A. (2015). Electrocortical dynamics in children with a language-learning impairment before and after audiovisual training. Brain Topography: 29(3): 459-476. doi: 10.1007/s10548-015-0466-y
Musacchia, G., Ortiz-Mantilla, S., Realpe-Bonilla, T., Roesler, C., & Benasich, A.A. (2015). Infant auditory processing and event-related brain oscillations. J. Vis. Exp.: e52420. doi:10.3791/52420.
Heim, S., Benasich, A.A., Wirth, N., & Keil, A. (2015). Tracking the attentional blink profile: a cross-sectional study from childhood to adolescence. Psychological Research, 79(1), 19-27. doi: 10.1007/s00426-013-0530-8
Choudhury, N.A., Parascando, J.A., & Benasich, A.A. (2015). Mismatch responses in school-age children and adults: Effects of rate of presentation and attention. PLOS One, 10(9) doi: 10.1371/journal.pone.0138160
2014
Benasich, A.A., Choudhury, N.A., Realpe-Bonilla, T., & Roesler, C.P. (2014). Plasticity in developing brain: Active auditory exposure impacts prelinguistic acoustic mapping. The Journal of Neuroscience, 34(40), 13349-13363. doi:10.1523/jneurosci.0972-14.2014
2013
Roesler, C.P., Flax, J., MacRoy-Higgins, M. , Fermano, Z.,Morgan-Byrne, J. & Benasich, A.A. (2013). Sensory Desensitization Training for Successful Net Application and EEG/ERP Acquisition in Difficult to Test Children. Communication Disorders Quarterly, 35(1), 14-20. doi: 10.1177/1525740113489167
Ortiz-Mantilla, S., Hämäläinen, J.A., Musacchia, G., & Benasich, A.A. (2013). Enhancement of Gamma oscillations indicates preferential processing of native over foreign phonetic contrasts in infants. Journal of Neuroscience, 33(48), 18746-54. doi: 10.1523/jneurosci.3260-13.2013
Musacchia, G., Choudhury, N.A., Ortiz-Mantilla, S., Realpe-Bonilla, T., Roesler, C.P., & Benasich, A.A. (2013). Oscillatory support for rapid frequency change processing in infants. Neuropsychologia, 51(13), 2812-2824. doi: 10.1016/j.neuropsychologia.2013.09.006.
Heim, S., Benasich, A.A., & Keil, A. (2013). Distraction by emotion in early adolescence: affective facilitation and interference during the attentional blink. Front Psychol., 4, 580. doi: 10.3389/fpsyg.2013.00580.
Ortiz-Mantilla, S., & Benasich, A.A. (2013). Neonatal electrophysiological predictors of cognitive and language development. Dev Med Child Neurol., 55(9), 781-2. doi: 10.1111/dmcn.12207.
Heim S., Keil A., Choudhury, N., Thomas Friedman, J., & Benasich, A.A. (2013). Early gamma oscillations during rapid auditory processing in children with a language-learning impairment: changes in neural mass activity after training. Neuropsychologia, 51(5), 990-1001. doi: 10.1016/j.neuropsychologia.2013.01.011.
2012
Choe, M.S., Ortiz-Mantilla, S., Makris, N., Gregas, M., Bacic, J., Haehn, D., Kennedy, D., Pienaar, R., Caviness, V.S. Jr., Benasich, A.A., & Grant, P.E. (2013). Regional infant brain development: an MRI-based morphometric analysis in 3 to 13 month olds. Cerebral Cortex, 23(9), 2100-17. doi: 10.1093/cercor/bhs197.
Raschle, N., Zuk, J., Ortiz-Mantilla, S., Sliva, D., Franceschi, A., Grant, P.E., Benasich, A.A., & Gaab, N. (2012). Pediatric neuroimaging in early childhood and infancy: Challenges and practical guidelines. Annals of the New York Academy of Sciences, 1252, 43-50. doi: 10.1111/j.1749-6632.2012.06457.x.
Ortiz-Mantilla, S., Hämäläinen, J.A., & Benasich, A.A. (2012). Time course of ERP generators to syllables in infants: A source localization study using age-appropriate brain templates. NeuroImage, 59, 3275-3287. doi:10.1016/j.neuroimage.2011.11.048
2011
Heim, S., Friedman, J.T., Keil, A., & Benasich, A.A. (2011). Reduced sensory oscillatory activity during rapid auditory processing as a correlate of language-learning impairment. Journal of Neurolinguistics, 24(5), 539-555. doi:10.1016/j.jneuroling.2010.09.006
Hämäläinen, J.A., Ortiz-Mantilla, S., & Benasich, A.A. (2011). Source localization of event-related potentials to pitch change mapped onto age-appropriate MRIs at 6 months of age. NeuroImage, 54(3), 1910-1918. doi:10.1016/j.neuroimage.2010.10.016
Gou, Z., Choudhury, N. & Benasich, A.A. (2011). Resting frontal gamma power at 16, 24 and 36 months predicts individual differences in language and cognition at 4 and 5 years. Behavioral Brain Research, 220(2), 263-70. doi:10.1016/j.bbr.2011.01.048
Choudhury, N., & Benasich, A.A. (2011). Maturation of Auditory Evoked Potentials from 6 to 48 months: Prediction to 3 and 4 year Language and Cognitive Abilities. Clinical Neurophysiology, 122(2), 320-338. doi:10.1016/j.clinph.2010.05.035
2010
Ortiz-Mantilla, S., Choudhury, N., Alvarez, B., & Benasich, A.A. (2010). Involuntary switching of attention mediates differences in event-related responses to complex tones between early and late Spanish-English bilinguals. Brain Research, 1362, 78-92. doi: 10.1016/j.brainres.2010.09.031.
Ortiz-Mantilla, S., Choe, M.S., Flax, J., Grant, P.E., & Benasich, A.A. (2010). Association between the size of the amygdala in infancy and language abilities during the preschool years in normally developing children. NeuroImage, 49, 2791-2799. doi: 10.1016/j.neuroimage.2009.10.029.
2009
Choudhury, N. & Benasich, A.A. (2009). Infant information processing and family history of specific language impairmet: Converging evidence for early auditory perceptual deficits. In H. Eswaran, & N. Chatterje Singh (Eds.), Advances in developmental neuroscience and imaging, (pp. 9-23). New Delhi, India: Anamaya Publishers.
Flax. J. F, Realpe-Bonilla, T., Roesler, C., Choudhury, N., & Benasich A.A. (2009). Using early standardized language measures to predict later language and early reading outcomes in children at high risk for language-learning impairments. Journal of Learning Disabilities, 42, 61-75. doi: 10.1177/0022219408326215
2008
Benasich, A.A., Gou, Z., Choudhury, N., & Harris, K. D. (2008). Early Cognitive and Language Skills are Linked to Resting Frontal Gamma Power Across the First Three Years. Behavioral Brain Research, 95(2), 215-22. doi: 10.1016/j.bbr.2008.08.049.
Liu, W-C., Flax, J.F., Guise, K.G., Sukul, V., & Benasich, A.A. (2008). Functional Connectivity of the Sensorimotor Area in Naturally Sleeping Infant. Brain Research, 5(1223), 42-9. https://doi.org/10.1016/j.brainres.2008.05.054.
Ortiz-Mantilla, S., Choudhury, N., Leevers, H., & Benasich, A.A. (2008) Understanding language and cognitive effects in Very Low Birth Weight infants. Dev Psychobiology, 50(2), 107-126. doi: 10.1002/dev.20278.
Wang, Z., Fernandez-Seara, M., Alsop, D.C., Liu, W-C., Flax, J.F., Benasich, A.A., & Detre, J.A. (2008). Assessment of Functional Development in Normal Infant Brain using Arterial Spin Labeled Perfusion MRI. NeuroImage, 39(3), 973-978. doi: 10.1016/j.neuroimage.2007.09.045.
2007
Nawyn, J., Roesler, C., Realpe-Bonilla, T., Choudhury, N., & Benasich, A.A. (2007). An operantly conditioned looking task for assessing infant auditory processing ability. (Technical Paper) In Proceedings of the 9th International ACM SIGACCESS Conference on Computers and Accessibility. ASSETS '07, ACM, New York, NY, 147-154. doi: 10.1145/1296843.1296869
Choudhury, N., Leppänen, P.H.T., Leevers, H.J., & Benasich, A.A. (2007). Infant information processing and family history of specific language impairment: Converging evidence for RAP deficits from two paradigms. Developmental Science, 10(2), 213-236. doi: 10.1111/j.1467-7687.2007.00546.x
2006
Heim, S. & Benasich, A.A. (2006). Disorders of language. In D. Cicchetti, & D. Cohen (Eds.), Developmental Psychopathology, 2nd Edition, (pp. 268-316). New York: John Wiley & Sons.
Paterson, S.J., Heim, S., Friedman, J.T., Choudhury, N., & Benasich, A.A. (2006). Development of structure and function in the infant brain: Implications for cognition, language and social behaviour. Neuroscience and Biobehavioral Reviews, 30, 1087-1105. doi: 10.1016/j.neubiorev.2006.05.001
Roesler, C., Paterson, S.J., Flax, J., Hahn, J.S., Kovar, C., Stashinko, E., Jing, H., & Benasich, A.A. (2006). Cognitive Profile of Children with Holoprosencephaly. Pediatric Neurology, 35, 387-394. doi: 10.1016/j.pediatrneurol.2006.07.004
Jing, H., & Benasich, A. A. (2006). Brain Responses to tonal changes in the first two years of life. Brain & Development, 28(4), 247-56. doi: 10.1016/j.braindev.2005.09.002
Jing, H., Flax, J., Roesler, C., Choudhury, N., & Benasich, A.A. (2006). Auditory event-related responses in children with semi-lobar holoprosencephaly. Brain & Development, 28(4), 207-214. doi: 10.1016/j.braindev.2005.07.005
Benasich, A.A., Choudhury, N., Friedman, J.T., Realpe Bonilla, T., Chojnowska, C., & Gou, Z. (2006). Infants as a prelinguistic model for language learning impairments: Predicting from event-related potentials to behavior. Neuropsychologia, 44(3), 396-411. doi: 10.1016/j.neuropsychologia.2005.06.004
2005
Leevers, H.J., Roesler, C., Flax, J., & Benasich, A.A., (2005). The Carter Neurocognitive Assessment: Evaluation of children with severe expressive language and motor impairment. Journal of Child Psychology and Psychiatry, 46(3), 1-17. doi: 10.1111/j.1469-7610.2004.00354.x
2004
Leppanen, P. H. T., Choudhury, N., Benasich, A. A. & Lyytinen, H. (2004). Neuroimaging measures in the study of specific language impairment. In L. Verhoeven, & H. van Balkom (Eds.) Classifications of developmental language disorders: Theoretical issues and clinical implications. (pp. 99-137). Mahwah, NJ: Lawrence Elrbaum Press.
Friedman, J.T., Peiffer, A.M., Clark, M.G, Benasich, A.A., & Fitch, R.H. (2004). Age and experience-related improvements in gap detection in the rat. Developmental Brain Research, 152(2), 83-91. doi: 10.1016/j.devbrainres.2004.06.007
Jing, H., Heim, S., Chojnowskia C., Thomas, J., & Benasich, A.A. (2004). Timing errors in auditory event-related potentials. Journal of Neuroscience Methods, 138(1-2), 1-6. doi: 10.1016/j.jneumeth.2004.03.009
2003
Choudhury, N., & Benasich, A.A. (2003). Familial aggregation in a sample of infants born into families with a history of language-based learning impairments. Journal of Speech, Language and Hearing Research, 46, 261-272. doi: 10.1044/1092-4388(2003/021)
Benasich, A.A., & Thomas, J.J. (2003). Developmental disorders of language. In L. Nadel (Ed.), Encyclopedia of Cognitive Science, Vol. 1 (pp. 959-967). London UK: Macmillan Reference Limited, Nature Publishing Group.
2002
Benasich, A.A., & Leevers, H.J. (2002). Processing of rapidly presented auditory cues in infancy: Implications for later language development. In J. Fagan, & H. Haynes (Eds.), Progress in Infancy Research, Vol. 3. (pp. 245-288). Mahwah, NJ: Lawrence Erlbaum Associates, Inc. (peer-reviewed edited annual volume).
Benasich, A.A., & Tallal, P. (2002). Infant discrimination of rapid auditory cues predicts later language impairment. Behavioral Brain Research, 136(1), 31-49. doi: 10.1016/s0166-4328(02)00098-0.
Tallal, P., & Benasich, A.A. (2002). Language Learning Disabilities. Development and Psychopathology, 14, 559-579. doi: 10.1017/s0954579402003097.
Benasich, A.A. (2002). Impaired processing of brief, rapidly presented auditory cues in infants with a family history of autoimmune disorder. Developmental Neuropsychology, 22(1), 351-372. doi: 10.1207/S15326942dn2201_2.
Jing, H., Takigawa, M., & Benasich, A.A. (2002). Relationship of nonlinear analysis, MRI and SPECT in the lateralization of temporal lobe epilepsy, European Neurology, 48(1), 11-19. doi: 10.1159/000064951.
Benasich, A.A., Thomas, J.J., Choudhury, N., & Leppänen, P.H.T. (2002). The importance of rapid auditory processing abilities to early language development: Evidence from converging methodologies. Developmental Psychobiology, 40, 278-292. doi: 10.1002/dev.10032.
2001
Fitch, R.H., Read, H., & Benasich, A.A. (2001). Neurophysiology of speech perception in normal and impaired systems. In A. Jahn, & J. Santos-Sacchi (Eds.), Physiology of the ear, 2nd edition, (pp. 651-672). San Diego: Singular Publishing Group, Inc.
1999
Benasich, A.A. (1999). Temporal integration as an early predictor of speech and language development. In C. von Euler, I. Lundberg, & R. Llinás (Eds.), Basic Mechanisms In Cognition And Language - With Special Reference To Phonological Problems In Dyslexia (pp. 123-142). Oxford: Elsevier Science Ltd.
Benasich, A.A., & Spitz, R.V. (1999). Insights from infants: Temporal processing abilities and genetics contribute to language development. In K. Whitmore, H. Hart, & G. Willems (Eds.), A Neurodevelopmental Approach to Specific Learning Disorders (pp. 191-210). London: Mac Keith Press.
1998
Benasich, A.A., & Read, H. (1998). Representation: Picture or process? In I.E. Sigel (Ed), Theoretical perspectives in the development of representational (symbolic) thought (pp. 33-160). Mahwah, NJ: Lawrence Erlbaum Associates, Inc.
1997
Spitz, R.V., Tallal, P., Flax, J., & Benasich, A.A. (1997). Look who's talking: A prospective study of familial transmission of language impairments. Journal of Speech and Hearing Research, 40, 990-1001. doi: 10.1044/jslhr.4005.990.
1996
Benasich, A.A., & Tallal, P. (1996). Auditory Temporal Processing Thresholds, Habituation, And Recognition Memory Over The First Year. Infant Behavior and Development, 19, 339-357. https://doi.org/10.1016/S0163-6383(96)90033-8
1993
Benasich, A. A., Curtiss, S., & Tallal, P. (1993). Language, learning, and behavioral disturbances in childhood: A longitudinal perspective. Journal of the American Academy of Child & Adolescent Psychiatry, 32(3), 585-594. doi: 10.1097/00004583-199305000-00015.