Recent Publications

Lab Publications


Jannesari M., Saeedi A., Zare M., Ortiz-Mantilla S., Plenz D., Benasich A.A. Stability of neuronal avalanches and long-range temporal correlations during the first year of life in human infants. Brain, Structure and Function doi: 10.1007/s00429-019-01918-5.

Hämäläinen J.A., Ortiz-Mantilla S., Benasich A.A. (2019). Change detection to tone pairs during the first year of life – Predictive longitudinal relationships for EEG-based source and time- frequency measures. NeuroImage. doi: 10.1016/j.neuroimage.2019.05.034.

Ortiz-Mantilla S., Cantiani C., Shafer V., & Benasich, A.A. (2019). Minimally-verbal children with autism show deficits in theta and gamma oscillations during processing of semantically-related visual information. Scientific Reports. doi: 10.1038/s41598-019-41511-8.

Cantiani C., Ortiz-Mantilla S., Riva V., Piazza C., Musacchia G., Molteni M., Marino C., & Benasich AA. (2019). Reduced left-lateralized pattern of event-related EEG oscillations in infants at familial risk for language and learning impairment. NeuroImage Clinical. doi: 10.1016/j.nicl.2019.101778.

Ortiz-Mantilla, S., Realpe-Bonilla, T., & Benasich, A. (2019). Early interactive acoustic experience with non-speech generalizes to speech and confers a syllabic processing advantage at 9 months. Cerebral Cortex, 29, 1789-1801. doi: 10.1093/cercor/bhz001

Musacchia G., Ortiz-Mantilla S., Roesler C.P., Rajendran S., Morgan-Byrne J., & Benasich A.A. (2018). Effects of noise and age on the infant brainstem response to speech. Clinical Neurophysiology, 129(12), 2623-2634. doi: 0.1016/j.clinph.2018.08.005

Koyama, M.S., Ortiz-Mantilla, S., Roesler, C.P., Milham, M.P., & Benasich, A.A. (2017). A modulatory effect of brief passive exposure to nonlinguistic sounds on intrinsic functional connectivity: Relevance to cognitive performance. Cerebral Cortex, 27, 5817-5830. doi: 10.1093/cercor/bhx266


Musacchia, G., Ortiz-Mantilla, S., Choudhury, N., Realpe-Bonilla, T., Roesler, C., & Benasich A.A. (2017). Active auditory exposure in infancy promotes brain plasticity in Theta and Gamma oscillations. Developmental Cognitive Neuroscience, 26, 9-19.


Riva, V., Cantiani, C., Benasich, A.A., Molteni, M., Piazza, C., Giorda, R., Dionne, G., & Marino, C. (2017). From CNTNAP2 to early expressive language in infancy: the mediation role of auditory processing. Cerebral Cortex, May 11, 2017, 1-9.

Past Publications


Benasich, A.A., Choudhury, N., Peters, S., & Ortiz-Mantilla, S. (2016). Early Screening and Intervention of Infants at High Risk for Developmental Language Disorders. International Dyslexia Association (IDA). Perspectives on Language and Literacy, Winter 2016, 24-29.


Ortiz-Mantilla, S., Hämäläinen, J.A., Realpe-Bonilla, T., & Benasich A.A. (2016). Oscillatory dynamics underlying perceptual narrowing of native phoneme mapping from 6 to 12 months of age. Journal of Neuroscience, 36(48), 12095-12105.


Zare, M., Rezvani, Z., & Benasich, A.A. (2016). Automatic classification of 6-month-old infants at familial risk for language-based learning disorder using support vector machine. Clinical Neurophysiology, 127, 2695-2703.


Cantiani, C., Choudhury, N.A., Yu, Y.H., Shafer, V., Schwartz, R.G., & Benasich, A.A. (2016). From sensory perception to lexical-semantic processing: An ERP study in non-verbal children with autism. PLOS ONE


Akalin-Acar, Z., Ortiz-Mantilla, S., Benasich, A.A., & Makeig, S. (2016). High-resolution EEG source imaging of one-year-old children. Engineering in Medicine and Biology Society (EMBC), 2016 IEEE 38th Annual International Conference 117-120. doi: 10.1109/EMBC.2016.7590654


Cantiani, C., Riva, V., Piazza, C., Bettoni, R., Molteni, M., Choudhury, N., Marino, C., & Benasich, A.A. (2016). Auditory discrimination predicts linguistic outcome in Italian infants with and without familial risk for language learning impairment. Developmental Cognitive Neuroscience, 20, 23-34.


Tozzi, A., Zare, M., & Benasich, A.A. (2016). New perspectives on spontaneous brain activity: dynamic networks and energy matter. Frontiers in Human Neuroscience, 94(8), 702-716. doi: 10.3389/fnhum.2016.00247.


Piazza, C., Cantiani, C., Akalin-Acar, Z., Miyakoshi, M., Benasich, A.A., Reni, G., Bianchi, A.M., & Makeig, S. (2016). ICA-derived cortical responses indexing rapid multi-feature auditory processing in six-month-old infants. NeuroImage, 133, 75-87.



Heim, S., Choudhury, N., & Benasich, A.A. (2015). Electrocortical dynamics in children with a language-learning impairment before and after audiovisual training. Brain Topography: 29(3): 459-476. doi: 10.1007/s10548-015-0466-y


Musacchia, G., Ortiz-Mantilla, S., Realpe-Bonilla, T., Roesler, C., & Benasich, A.A. (2015). Infant auditory processing and event-related brain oscillations.  J. Vis. Exp.: e52420. doi:10.3791/52420


Heim, S., Benasich, A.A., Wirth, N., & Keil, A. (2015). Tracking the attentional blink profile: a cross-sectional study from childhood to adolescence. Psychological Research, 79(1), 19-27.


Choudhury, N.A., Parascando, J.A., & Benasich, A.A. (2015). Mismatch responses in school-age children and adults: Effects of rate of presentation and attention. PLOS One, 10(9)  doi: 10.1371/journal.pone.0138160



Benasich, A.A.,  Choudhury, N.A., Realpe-Bonilla, T., & Roesler, C.P. (2014). Plasticity in developing brain: Active auditory exposure impacts prelinguistic acoustic mapping. The Journal of Neuroscience, 34(40), 13349-13363. doi:10.1523/jneurosci.0972-14.2014



Roesler, C.P., Flax, J., MacRoy-Higgins, M. , Fermano, Z.,Morgan-Byrne, J. & Benasich, A.A. (2013). Sensory Desensitization Training for Successful Net Application and EEG/ERP Acquisition in Difficult to Test Children. Communication Disorders Quarterly, 35(1), 14-20. doi: 10.1177/1525740113489167


Ortiz-Mantilla, S., Hämäläinen, J.A., Musacchia, G., & Benasich, A.A. (2013). Enhancement of Gamma oscillations indicates preferential processing of native over foreign phonetic contrasts in infants. Journal of Neuroscience, 33(48), 18746-54. doi: 10.1523/jneurosci.3260-13.2013


Musacchia, G., Choudhury, N.A., Ortiz-Mantilla, S., Realpe-Bonilla, T., Roesler, C.P., & Benasich, A.A. (2013). Oscillatory support for rapid frequency change processing in infants.  Neuropsychologia, 51(13), 2812-2824.  doi: 10.1016/j.neuropsychologia.2013.09.006.


Heim, S., Benasich, A.A., & Keil, A.  (2013). Distraction by emotion in early adolescence: affective facilitation and interference during the attentional blink.  Front Psychol., 4, 580. doi: 10.3389/fpsyg.2013.00580.


Ortiz-Mantilla, S., & Benasich, A.A. (2013). Neonatal electrophysiological predictors of cognitive and language development.  Dev Med Child Neurol., 55(9), 781-2. doi: 10.1111/dmcn.12207.


Heim S., Keil A., Choudhury, N., Thomas Friedman, J., & Benasich, A.A.  (2013). Early gamma oscillations during rapid auditory processing in children with a language-learning impairment: changes in neural mass activity after training.  Neuropsychologia, 51(5), 990-1001. doi: 10.1016/j.neuropsychologia.2013.01.011.



Choe, M.S., Ortiz-Mantilla, S., Makris, N., Gregas, M., Bacic, J., Haehn, D., Kennedy, D., Pienaar, R., Caviness, V.S. Jr., Benasich, A.A., & Grant, P.E. (2013).  Regional infant brain development: an MRI-based morphometric analysis in 3 to 13 month olds. Cerebral Cortex, 23(9), 2100-17. doi: 10.1093/cercor/bhs197.


Raschle, N., Zuk, J., Ortiz-Mantilla, S., Sliva, D., Franceschi, A., Grant, P.E., Benasich, A.A., & Gaab, N. (2012). Pediatric neuroimaging in early childhood and infancy: Challenges and practical guidelines.  Annals of the New York Academy of Sciences, 1252, 43-50. doi: 10.1111/j.1749-6632.2012.06457.x.


Ortiz-Mantilla, S., Hämäläinen, J.A., & Benasich, A.A. (2012). Time course of ERP generators to syllables in infants: A source localization study using age-appropriate brain templates. NeuroImage, 59, 3275-3287. doi:10.1016/j.neuroimage.2011.11.048



Heim, S., Friedman, J.T., Keil, A., & Benasich, A.A. (2011). Reduced sensory oscillatory activity during rapid auditory processing as a correlate of language-learning impairment. Journal of Neurolinguistics, 24(5), 539-555. doi:10.1016/j.jneuroling.2010.09.006


Hämäläinen, J.A., Ortiz-Mantilla, S., & Benasich, A.A. (2011). Source localization of event-related potentials to pitch change mapped onto age-appropriate MRIs at 6 months of age. NeuroImage, 54(3), 1910-1918. doi:10.1016/j.neuroimage.2010.10.016


Gou, Z., Choudhury, N. & Benasich, A.A. (2011). Resting frontal gamma power at 16, 24 and 36 months predicts individual differences in language and cognition at 4 and 5 years. Behavioral Brain Research, 220(2), 263-70. doi:10.1016/j.bbr.2011.01.048


Choudhury, N., & Benasich, A.A. (2011). Maturation of Auditory Evoked Potentials from 6 to 48 months: Prediction to 3 and 4 year Language and Cognitive Abilities.  Clinical Neurophysiology, 122(2), 320-338. doi:10.1016/j.clinph.2010.05.035



Ortiz-Mantilla, S., Choudhury, N., Alvarez, B., & Benasich, A.A. (2010). Involuntary switching of attention mediates differences in event-related responses to complex tones between  early and late Spanish-English bilinguals. Brain Research, 1362, 78-92. 


Ortiz-Mantilla, S., Choe, M.S., Flax, J., Grant, P.E., & Benasich, A.A. (2010). Association between the size of the amygdala in infancy and language abilities during the preschool years in normally developing children.  NeuroImage, 49, 2791-2799.



Choudhury, N. & Benasich, A.A. (2009). Infant information processing and family history of specific language impairmet: Converging evidence for early auditory perceptual deficits. In H. Eswaran, & N. Chatterje Singh (Eds.), Advances in developmental neuroscience and imaging, (pp. 9-23). New Delhi, India: Anamaya Publishers.


Flax. J. F, Realpe-Bonilla, T., Roesler, C., Choudhury, N., & Benasich A.A. (2009). Using early standardized language measures to predict later language and early reading outcomes in children at high risk for language-learning impairments. Journal of Learning Disabilities, 42, 61-75.



Benasich, A.A., Gou, Z., Choudhury, N., & Harris, K. D. (2008). Early Cognitive and Language Skills are Linked to Resting Frontal Gamma Power Across the First Three Years. Behavioral Brain Research, 95(2), 215-22.


Liu, W-C., Flax, J.F., Guise, K.G., Sukul, V., & Benasich, A.A. (2008). Functional Connectivity of the Sensorimotor Area in Naturally Sleeping Infant. Brain Research, 5(1223), 42-9.


Ortiz-Mantilla, S., Choudhury, N., Leevers, H., & Benasich, A.A. (2008) Understanding language and cognitive effects in Very Low Birth Weight infants. Dev Psychobiology, 50(2), 107-126.


Wang, Z., Fernandez-Seara, M., Alsop, D.C., Liu, W-C., Flax, J.F., Benasich, A.A., & Detre, J.A. (2008). Assessment of Functional Development in Normal Infant Brain using Arterial Spin Labeled Perfusion MRI, NeuroImage, 39(3), 973-978.



Nawyn, J., Roesler, C., Realpe-Bonilla, T., Choudhury, N., & Benasich, A.A. (2007). An operantly conditioned looking task for assessing infant auditory processing ability. (Technical Paper) In Proceedings of the 9th International ACM SIGACCESS Conference on Computers and Accessibility. ASSETS '07, ACM, New York, NY, 147-154.


Choudhury, N., Leppänen, P.H.T., Leevers, H.J., & Benasich, A.A. (2007). Infant information processing and family history of specific language impairment: Converging evidence for RAP deficits from two paradigms. Developmental Science, 10(2), 213-236.



Heim, S. & Benasich, A.A. (2006). Disorders of language. In D. Cicchetti, & D. Cohen (Eds.), Developmental Psychopathology, 2nd Edition, (pp. 268-316). New York: John Wiley & Sons.


Paterson, S.J., Heim, S., Friedman, J.T., Choudhury, N., & Benasich, A.A. (2006). Development of structure and function in the infant brain: Implications for cognition, language and social behaviour. Neuroscience and Biobehavioral Reviews, 30, 1087-1105.


Roesler, C., Paterson, S.J., Flax, J., Hahn, J.S., Kovar, C., Stashinko, E., Jing, H., & Benasich, A.A. (2006). Cognitive Profile of Children with Holoprosencephaly. Pediatric Neurology, 35, 387-394.


Jing, H., & Benasich, A. A. (2006). Brain Responses to tonal changes in the first two years of life. Brain & Development, 28(4), 247-56.


Jing, H., Flax, J., Roesler, C., Choudhury, N., & Benasich, A.A. (2006). Auditory event-related responses in children with semi-lobar holoprosencephaly. Brain & Development, 28(4), 207-214.


Benasich, A.A., Choudhury, N., Friedman, J.T., Realpe Bonilla, T., Chojnowska, C., & Gou, Z. (2006).  Infants as a prelinguistic model for language learning impairments: Predicting from event-related potentials to behavior. Neuropsychologia, 44(3), 396-411



Leevers, H.J., Roesler, C., Flax, J., & Benasich, A.A., (2005). The Carter Neurocognitive Assessment: Evaluation of children with severe expressive language and motor impairment.  Journal of Child Psychology and Psychiatry, 46(3), 1-17.



Leppanen, P. H. T., Choudhury, N., Benasich, A. A. & Lyytinen, H. (2004). Neuroimaging measures in the study of specific language impairment. In L. Verhoeven, & H. van Balkom (Eds.) Classifications of developmental language disorders: Theoretical issues and clinical implications. (pp. 99-137). Mahwah, NJ: Lawrence Elrbaum Press.


Friedman, J.T., Peiffer, A.M., Clark, M.G, Benasich, A.A., & Fitch, R.H. (2004). Age and experience-related improvements in gap detection in the rat. Developmental Brain Research, 152(2), 83-91.


Jing, H., Heim, S., Chojnowskia C., Thomas, J., & Benasich, A.A. (2004). Timing errors in auditory event-related potentials. Journal of Neuroscience Methods, 138(1-2), 1-6.



Choudhury, N., & Benasich, A.A. (2003). Familial aggregation in a sample of infants born into families with a history of language-based learning impairments. Journal of Speech, Language and Hearing Research, 46, 261-272.


Benasich, A.A., & Thomas, J.J. (2003). Developmental disorders of language.  In L. Nadel (Ed.),  Encyclopedia of Cognitive Science, Vol. 1 (pp. 959-967). London UK:  Macmillan Reference Limited, Nature Publishing Group.



Benasich, A.A., & Leevers, H.J. (2002). Processing of rapidly presented auditory cues in infancy: Implications for later language development.  In J. Fagan, & H. Haynes (Eds.), Progress in Infancy Research, Vol. 3. (pp. 245-288). Mahwah, NJ:  Lawrence Erlbaum Associates, Inc. (peer-reviewed edited annual volume).


Benasich, A.A., & Tallal, P. (2002). Infant discrimination of rapid auditory cues predicts later language impairment. Behavioral Brain Research, 136(1), 31-49 


Tallal, P., & Benasich, A.A. (2002). Language Learning Disabilities. Development and Psychopathology, 14, 559-579.


Benasich, A.A. (2002). Impaired processing of brief, rapidly presented auditory cues in infants with a family history of autoimmune disorder.  Developmental Neuropsychology, 22(1), 351-372.


Jing, H., Takigawa, M., & Benasich, A.A. (2002). Relationship of nonlinear analysis, MRI and SPECT in the lateralization of temporal lobe epilepsy, European Neurology, 48(1), 11-19.


Benasich, A.A., Thomas, J.J., Choudhury, N., & Leppänen, P.H.T.  (2002). The importance of rapid auditory processing abilities to early language development: Evidence from converging methodologies. Developmental Psychobiology, 40, 278-292.



Fitch, R.H., Read, H., & Benasich, A.A. (2001). Neurophysiology of speech perception in normal and impaired systems.  In A. Jahn, & J. Santos-Sacchi (Eds.), Physiology of the ear, 2nd edition, (pp. 651-672). San Diego:  Singular Publishing Group, Inc.



Benasich, A.A. (1999). Temporal integration as an early predictor of speech and language development.  In C. von Euler, I. Lundberg, & R. Llinás (Eds.), Basic Mechanisms In Cognition And Language - With Special Reference To Phonological Problems In Dyslexia (pp. 123-142). Oxford: Elsevier Science Ltd.


Benasich, A.A., & Spitz, R.V.  (1999).  Insights from infants: Temporal processing abilities and genetics contribute to language development. In K. Whitmore, H. Hart, & G. Willems (Eds.),  A Neurodevelopmental Approach to Specific Learning Disorders (pp. 191-210). London: Mac Keith Press.



Benasich, A.A., & Read, H. (1998). Representation:  Picture or process?  In I.E. Sigel (Ed),  Theoretical perspectives in the development of representational (symbolic) thought (pp. 33-160). Mahwah, NJ:  Lawrence Erlbaum Associates, Inc.



Spitz, R.V., Tallal, P., Flax, J., & Benasich, A.A. (1997).  Look who's talking: A prospective study of familial transmission of language impairments.  Journal of Speech and Hearing Research, 40, 990-1001.



Benasich, A.A., & Tallal, P. (1996). Auditory Temporal Processing Thresholds, Habituation, And Recognition Memory Over The First Year. Infant Behavior and Development, 19, 339-357.



Benasich, A. A., Curtiss, S., & Tallal, P. (1993). Language, learning, and behavioral disturbances in childhood: A longitudinal perspective. Journal of the American Academy of Child & Adolescent Psychiatry, 32(3), 585-594.